@article { author = {Mirfeizi, Zahra and Norouzbeigi, Nasim and Sahebari, Maryam and Jokar, Mohammadhassan and Rezaei Yazdi, Zahra and Zakavi, Seyed Rasoul and Shafiei, Sousan and Aghaee, Atena}, title = {Feasibility and Toxicity of Intra-Articular 188Re-tin Colloid Injection in Patients with Rheumatoid Arthritis with Three-Phase Positive Bone Scan and Refractory Knee Pain, a pilot study}, journal = {Rheumatology Research}, volume = {5}, number = {3}, pages = {99-103}, year = {2020}, publisher = {Rheumatology Research}, issn = {2476-5856}, eissn = {2476-5856}, doi = {10.22631/rr.2020.69997.1098}, abstract = {Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that causes chronic synovial inflammation. Reactor-producedĪ²-particle emitting radionuclides is a new therapeutic strategy in the management of RA. This study was conducted in 2019and analyzed the toxicity and feasibility of 188Re-tin colloid injection, Three-Phase Positive Bone Scan, and Refractory KneePain. Ten patients with RA were administered radiosynovectomy with 188Re-tin colloid. The main complications after theintervention were assessed and compared with patientsā€™ pre-intervention condition. Patients showed alleviation of pain,tenderness, and morning stiffness after the administration of radiosynovectomy. Only one RA patient received a corticosteroidinjection; the other 6 patients did not need a corticosteroid injection after radiosynovectomy. Intra-articular 188Re-tin colloidinjection seems to be an effective treatment modality for refractory knee joint pain in rheumatoid arthritis patients. Thus, it issuggested as a safe and effective strategy to apply.}, keywords = {Knee joint,Pain,Rheumatoid arthritis,188Re-tin}, url = {https://www.rheumres.org/article_129528.html}, eprint = {https://www.rheumres.org/article_129528_a7ea37c0acabac65ef12877bebf3a5d9.pdf} }