Document Type: Case Report

Authors

1 Toxoplasmosis Research Center, Department of Radiology, Mazandaran University of Medical Sciences, Sari, Iran.

2 Gut and Liver Research center, Department of pathology, Mazandaran University of Medical Sciences, Sari, Iran.

3 Pulmonary and critical care division, Department of Internal Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

4 Diabetes Research Center, Department of Internal Medicine, Mazandaran University of Medical Sciences,Sari, Iran.

Abstract

Granulomatosis with polyangiitis vasculitis (GPA), or formerly known as Wegener’s Granulomatosis (WG) and sarcoidosis are two distinct granulomatous diseases characterized by multisystem involvement. The sequential development of these two diseases is very rare. We report a patient who initially exhibited the symptoms of sarcoidosis and then limited GPA, predominantly affecting the nose and paranasal sinus, which was histologically proven. Imaging, pathological, and laboratory findings were described. After treatment, controlled clinical symptoms and changes in laboratory findings and imaging were demonstrated.

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