SLE (Systemic Lupus Erythematosus) is an autoimmune disorder with a range of symptoms and an unclear cause. Infections,
which are one of the leading causes of death in SLE patients, are made more possible by immunosuppressive medications. It is
yet unclear how Cytomegalovirus (CMV) infection affects SLE. Clinically, differentiating between an infection and a lupus
flare-up is critical. For this reason, we discuss the case of a 56-year-old woman who was hospitalized to Loghman Hospital's
rheumatic clinic with SLE and CMV infection.