Aim and Background: Cutaneous Leishmaniasis (CL) is the most prevalent type of leishmaniasis. Iran is among the first six countries in the world with the highest annual incidence of CL. Non-caseating granulomatous inflammatory cutaneous reaction is the most patterns of its skin lesions. The aim is presentation of a 36 years old man with a history of PAN vasculitis with extensive caseating granulomatous lesions who diagnosed as Cutaneous Leishmaniasis.
Conclusion: caseating granulomatous could present in CL, so it is recommended to consider leishmaniasis in diagnosis of this histological pattern, especially in autoimmune patients before starting immunosuppressive treatment.