TY - JOUR ID - 42396 TI - Autoimmune polyendocrine syndrome type IIIC and ankylosing spondylitis: a case report JO - Rheumatology Research JA - RR LA - en SN - AU - Javinani, Ali AU - Aghaei Meybodi, Hamid Reza AU - Jamshidi, Ahmad Reza AU - Gharibdoost, Farhad AU - Kavosi, Hoda AD - Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran Y1 - 2017 PY - 2017 VL - 2 IS - 1 SP - 39 EP - 43 KW - ankylosing KW - autoimmune KW - Hashimoto disease KW - hypoparathyroidism KW - polyendocrinopathies KW - primary ovarian insufficiency KW - spondylitis DO - 10.22631/rr.2017.69997.1015 N2 - Autoimmune polyendocrine syndrome (APS) is an autoimmune disorder defined by multiple endocrinopathies and the presence of other systemic or organ-specific autoimmunities. This case study, reports on a 46-year-old woman with confirmed idiopathic hyperparathyroidism, who was referred for inflammatory back pain. HLA-B27 positivity, recurrent anterior uveitis and radiologic findings led to ankylosing spondylitis (AS) diagnosis. By further investigations, a subclinical atrophic autoimmune thyroid disease (AITD) was also diagnosed for her in addition to a history of premature ovarian failure. According to the absence of adrenal insufficiency in addition to an AITD and systemic autoimmune disorder, APS type IIIC was the most probable diagnosis. To the best of our knowledge, this is the first case report of APS type III associated with AS. UR - https://www.rheumres.org/article_42396.html L1 - https://www.rheumres.org/article_42396_83447e52439cd2398bf4bfe479e84f7a.pdf ER -