Document Type : Original Article
- Rabeah Rajabzadeh 1
- Seyed Reza Najafizadeh 1
- Shafieh Movassaghi 1
- Sara Jalali-Jivan 1
- Abdolrahman Rostamian 2
1 Department of Rheumatology, Imam Khomeini Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
2 Department of Rheumatology, Imam Khomeini Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Rheumatology Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Vasculitis is a rare disease and its prevalence varies according to age, race, time, and geographical location. The need for this study
is felt due to the fact that no study has been conducted in Iran to investigate the frequency, clinical, and laboratory symptoms of
vasculitis in the considerable population of vasculitis patients. The aim of this study was to evaluate the frequency and clinical
signs of granulomatosis with polyangiitis (GPA) patients who were admitted to the rheumatology ward in Valiasr Hospital, Tehran,
Iran, over the last 10 years.
In this study, all patients were evaluated with a possible diagnosis of vasculitis having been admitted to the rheumatology ward of
Valiasr Hospital over the past ten years. These GPA patients were evaluated for clinical, laboratory, radiological, and pathological
findings, as well as for outcome, mortality, and major complications.
Over the last 10 years, 223 vasculitis patients have been admitted to Valiasr Hospital and of these, 87% were primary vasculitis and
13% were secondary vasculitis. The highest frequency was related to GPA (21.52%) followed by Behcet's disease. GPA patients
were women and men at 52.08% and 47.91%, respectively. Upper and lower airway involvement and total ear, nose, and throat
(ENT) involvement was the most common clinical symptoms in GPA patients.
According to the findings of this study, GPA vasculitis was the most common type of vasculitis and ENT involvements were the
most common clinical symptoms in this patient. However, more studies are required to confirm these data in Iran.