Background: Fibromyalgia (FM) is a chronic musculoskeletal disorder characterized by widespread, long-term pain and multiple tender points revealed in physical examination. Previous studies about the relationship between serum vitamin D level and FM have reported paradoxical results. This cross-sectional study aimed to evaluate the level of vitamin D and its relationship with the severity of FM.
Methods: Based on American College of Rheumatology (ACS) criteria, 100 female patients with FM were enrolled in this study, and serum vitamin D levels were screened. Vitamin D deficiency is defined as a level less than 12 ng/mL,insufficiency is defined as levels between 12–29 ng/mL and sufficiency is a level equal to or less than 30 ng/mL. Disease severity was evaluated by symptom severity scale score (SSSS) and documented using designed questionnaires.
Results: Mean age of patients was 35/60 years. 47% of patients had vitamin D deficiency, 36 % had vitamin D insufficiency, and only 17 % had normal vitamin D serum levels. Vitamin D deficiency was reported among 50% of patients with SSS score between 9 and 12, 49% of patients with SSS score between 5 and 8, and 14/3% of patients with SSS score between 1 and 4. There was no significant correlation between the age of patients and vitamin D levels (P value=0.12). Also, There was no significant correlation between the age of patients and SSS score (P value=0.36).
Conclusion: Our study demonstrated that there was no statistically significant relationship between FM disease activity and vitamin D serum level.