Document Type : Case Report
Authors
1 Health Research Center, Life style institute, Department of Rheumatology, Baqiyatallah University of Medical Sciences, Tehran, Iran.
2 Chemical Injuries Research Center, Department of Rheumatology, Baqiyatallah University of Medical Sciences, Tehran, Iran.
3 Health Research Center, Department of Radiology, Baqiyatallah University of Medical Sciences, Tehran, Iran.
4 Health Management Research Center, Department of community medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Abstract
A 56 year old woman who had been coughing since 7 weeks ago, brought to the hospital on April 21 following the weakness feeling at the lower extremities and then in the upper extremities and he weakness gradually increased. Reverse transcription polymerase chain reaction (RT‐PCR) testing of coronavirus disease of 2019 (COVID-19) was performed and it was positive. COVID-19 Ig G was positive. Computed Tomography (CT) scan of the chest showed patchy ground glass opacities in the lungs. Muscle enzymes, Aldolase were elevated. Muscle MRI showed defined hyper intensity and edema in proximal muscles. Immune mediated necrotizing myositis was recommended in this patient that may have developed following SARS-Cov-2. Treatment started with methylprednisolone pulse and Intravenous immune globulin (IVIG). Following the start of treatment, the patient's dyspnea and muscles weakness improved. Although IMNM is a rare condition, especially in SARS-Cov-2, it is rapidly debilitating and physicians need to be more aware of the clinical and paraclinical features and therapeutic approach of IMNM.
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