Document Type : Case Report

Authors

• Hamidreza Soltani ¹
• Abdolrahim Sadeghi ²
• mohammad bagher Owlia ³
• Hamidreza Bashiri ¹

¹ Rheumatology Department, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

² Division of Radiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

³ Division of Rheumatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract

Hemophagocytic lymphohistiocytosis (HLH), is a disorder seen more often in children and is life-threatening in terms of over- activation of macrophages, and T cells resulting in cytokine storm. HLH can be familial or secondary to infections,malignancy, immunosuppression, and autoimmune conditions, such as systemic lupus erythematosus (SLE). Here, we report a 10-year old female with previously diagnosed SLE who hospitalized because of fever and pancytopenia.

Keywords

• Systemic lupus erythematosus
• Hemophagocytic lymphohistiocytosis (HLH)
• Cytokine storm
• Pancytopenia

Main Subjects

• Rheumatology